Compression Socks for Chronic Pain and Fatigue

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Last Updated on April 14, 2025 by melissanreynolds

We all know that compression socks are great for air travel. But did you know that compression socks can help with chronic pain and fatigue?

compression socks for chronic pain and fatigue

When I went to Disney with my family, I knew I’d need to stand and walk for long periods of time. Things that are hard for me to do. So I decided to wear my compression socks.

They worked shockingly well.

I did double my daily steps and was not incapacitated each evening with the agonizing muscular pains that usually occur. I was thankful and curious.

So I did some research on compression socks for chronic pain and fatigue. Here’s what I found.

Compression socks can improve circulation

Compression socks promote better blood flow by applying gentle pressure to the legs, which helps prevent blood pooling in the lower extremities. This can be especially beneficial for orthostatic intolerance, reducing symptoms like dizziness and lightheadedness when standing.

Improved circulation means oxygenated blood reaches your muscles and tissues more efficiently, reducing inflammation and promoting healing in areas that may be sore or painful.

Better circulation means that oxygen and nutrients are delivered more effectively to your muscles and tissues, preventing the “heavy leg” feeling and reducing overall fatigue.

Compression socks support blood pressure regulation

By improving venous return (blood flow back to the heart), compression socks can help stabilize blood pressure. This can alleviate some of the cardiovascular challenges associated with orthostatic intolerance and POTS (postural orthostatic tachycardia syndrome), which are often seen in people with HSD and CFS.

For those with dysautonomia (common in HSD and orthostatic intolerance), compression socks help minimize blood pooling in the legs, which can reduce the aching, throbbing sensations often caused by poor circulation.

Compression socks reduce leg swelling and fatigue

Many people with HSD and CFS experience swelling in the legs or feet, particularly after standing or sitting for long periods. Compression socks can minimize this swelling and reduce feelings of heaviness or fatigue in the legs.

Compression socks manage pain and discomfort

Compression socks can provide gentle support to muscles and joints, which may help reduce pain or discomfort in hypermobile joints and muscles. This can be particularly useful during or after physical activity.

Compression socks help reduce muscle vibration and oscillation caused by movement. This is especially helpful for people with hypermobility, whose muscles may be working overtime to compensate for joint instability. Less muscle strain means less soreness, which is beneficial during recovery after physical activity or prolonged standing.

Compression socks can boost energy levels

By improving circulation and reducing pooling of blood in the legs, compression socks may help improve overall energy levels.

When blood pools in the legs (a common issue in orthostatic intolerance), it can reduce blood supply to the brain, leading to lightheadedness, brain fog, and fatigue. Compression socks prevent this pooling, helping you feel more alert and less drained.

By reducing the physical toll of standing or sitting upright for long periods, compression socks can indirectly conserve energy.

Compression socks enhance recovery (and reduce post-exertion malaise)

Compression socks can aid muscle recovery by reducing soreness and improving circulation post-activity.

For those with CFS or HSD, overexertion can lead to post-exertional malaise (PEM)—a worsening of symptoms after activity. Compression socks, by supporting circulation and reducing muscle strain, may help delay or lessen the onset of PEM, leaving you with more energy for longer.

Tips for Choosing and Using Compression Socks:

Compression Level: Start with mild to moderate compression (15–20 mmHg) and adjust based on comfort and your healthcare provider’s advice.
Length: Knee-high socks are often sufficient, but thigh-high or full-length stockings may be better for severe symptoms.
Fit and Comfort: Ensure the socks fit well without being too tight. Poorly fitted socks can worsen discomfort.

There are many types, so you might like to look at what will suit you. Ensure you take the correct measurements so you don’t end up with too tight or too loose socks.

Here are some like mine (please note that I keep the top beneath my knees as I can’t stand pressure in that area). Affiliate notice: this link is an affiliate link, if you make a purchase using this link, I may make a small commission at no extra cost to you.

Practical Tips for Using Compression Socks

Timing: Put on compression socks before getting out of bed in the morning. This can prevent blood pooling from starting, especially if mornings are your hardest time. I use compression socks when I am doing additional physical activity.

Combine with Pacing: Use compression socks alongside pacing strategies to avoid overexertion and manage energy more effectively.

Hydration and Electrolytes: Compression socks work best when combined with proper hydration and salt intake, as these further support circulation and blood pressure.